| CAS NO: | 71079-09-9 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 71079-09-9 |
| Canonical SMILES | O=C(O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O |
| 分子式 | C17H19N3O7S |
| 分子量 | 409.41 |
| 溶解度 | DMSO: 20 mg/mL (48.85 mM; ultrasonic and adjust pH to 5 with HCl); Water:< 0.1 mg/mL (insoluble) |
| 储存条件 | 4℃, away from moisture |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | FOY 251 is an anti-proteolytic active metabolite camostate , acts as a proteinase inhibitor[1][2].FOY 251 inhibit SARS-CoV-2 infection in cells assay[1][3]. FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells[2].FOY-251 inhibits the proteolytic activity of prostasin[2]. [1]. K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and Its Degradation Products by the Rat Liver. Res Exp Med (Berl). 1987;187(6):401-6. [2]. Ai Maekawa, et al. Camostat Mesilate Inhibits Prostasin Activity and Reduces Blood Pressure and Renal Injury in Salt-Sensitive Hypertension. J Hypertens . 2009 Jan;27(1):181-9. [3]. Markus Hoffmann, et al. Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. bioRxiv. 2020 Aug 5;2020.08.05.237651. |
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