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Ac-LEHD-AMC(trifluoroacetate salt)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ac-LEHD-AMC(trifluoroacetate salt)图片
CAS NO:292633-16-0
包装与价格：
包装价格(元)
500μg电议
1mg电议
5mg电议

产品介绍
Ac-LEHD-AMC（三氟乙酸盐）是 caspase-9 的荧光底物（激发波长:341 nm；发射波长:441 nm）。
Cas No.292633-16-0
化学名N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine, trifluoroacetate salt
Canonical SMILESCC(C1=CC=C(C=C1O2)NC([C@@H](NC([C@H](CC3=CN=CN3)NC([C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)CCC(O)=O)=O)=O)CC(O)=O)=O)=CC2=O.FC(F)(C(O)=O)F
分子式C33H41N7O11.XCF3COOH
分子量711.7
溶解度1mg/mL in water
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9.[1] Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

References
[1]. Prudnikov, I.M., and Smirnov, A.N. Short peptide tools for monitoring caspase and proteasome activities in embryonal and adult rat brain lysates: An approach for the differential identification of proteases. J. Biochem. 151(3), 299-316 (2012).