Pipamperone

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Pipamperone

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1893-33-0

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
50mg	电议

产品介绍

Pipamperone (Floropipamide; McN-JR 3345; R 3345) 是 5-HT2A 受体 (pKi=8.2) 和 D4 受体 (pKi=8.0) 的高亲和力拮抗剂。Pipamperone (Floropipamide; McN-JR 3345; R 3345) 是 D2 受体 (pKi=6.7) 的低亲和力拮抗剂。

Cas No.	1893-33-0
别名	酰胺哌啶酮,Floropipamide; McN-JR 3345; R 3345
Canonical SMILES	O=C(C1(N2CCCCC2)CCN(CCCC(C3=CC=C(F)C=C3)=O)CC1)N
分子式	C₂₁H₃₀FN₃O₂
分子量	375.48
溶解度	0.1 M HCL: 25 mg/mL (66.58 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Pipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0) and a low-affinity antagonist of D2 receptor (pKi=6.7)[1]. 5-HT2A Receptor\|8.2 (pKi)\|5-HT2C Receptor\|6.9 (pKi)\|5-HT1 Receptor\|5.7 (pKi)\|D4 receptor\|8.0 (pKi)\|D2 receptor\|6.7 (pKi)\|α1 receptor\|7.2 (pKi) [1]. Erik Buntinx, MD, et al. Selective Serotonergic Properties of Low-Dose Pipamperone May Enhance Antidepressant Effect: Preclinical Evidence.