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3,4-Dihydroquinolin-2(1H)-one
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3,4-Dihydroquinolin-2(1H)-one图片
CAS NO:553-03-7
包装与价格：
包装价格(元)
1 g电议
5 g电议
10 g电议
25 g电议

产品介绍
A building block
Cas No.553-03-7
别名3,4-二氢-2(1H)-喹啉酮
Canonical SMILESO=C1NC2=C(CC1)C=CC=C2
分子式C9H9NO
分子量147.2
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3,4-Dihydroquinolin-2(1H)-one is a building block.1,2It has been used in the synthesis of compounds with antidepressant and anticonvulsant activities, as well as dual ligands of sigma (σ) receptors and the NMDA receptor GluN2b subunit that have antioxidant and neuroprotective properties.

1.Deng, X.-Q., Song, M.-X., Zheng, Y., et al.Design, synthesis and evaluation of the antidepressant and anticonvulsant activities of triazole-containing quinolinonesEur. J. Med. Chem.73217-224(2014) 2.Zampieri, D., Fortuna, S., Calabretti, A., et al.Discovery of new potent dual sigma receptor/GluN2b ligands with antioxidant property as neuroprotective agentsEur. J. Med. Chem.180268-282(2019)