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Z-VAD-FMK(Caspase Inhibitor VI)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Z-VAD-FMK(Caspase Inhibitor VI)图片
CAS NO:161401-82-7
规格:≥98%
包装与价格：
包装价格(元)
2mg电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)453.46
FormulaC21H28FN3O7
CAS No.161401-82-7
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 90 mg/mL (198.47 mM)
Water:<1 mg/mL (slightly soluble or insoluble)
Ethanol: N/A
SMILESO=C(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(CF)=O)=O)=O)C(C)C)OCC1=CC=CC=C1
Chemical NameZ-VAD(OH)-FMK; Z-VAD FMK L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-
实验参考方法
In VitroZ-VAD(OH)-FMK is the non-methylated form of Z-VAD-FMK, and useful in studies including recombinant, or purified enzymes. As an irreversible general caspase inhibitor, it is useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I, this inhibitor does not require pretreatment with esterase for in vitro studies. A 10 mM (1 mg/221 μl) solution of Caspase Inhibitor VI in DMSO is also available.
In VivoN/A
Animal modelN/A
Formulation & DosageN/A
ReferencesGarcia-Calvo M, et al. J Biol Chem. 1998, 273(49), 32608-32613.

生物活性

Inhibition of caspases by tetrapeptide aldehydes. J Biol Chem. 1998 Dec 4;273(49):32608-13.

Inhibition of caspases by CrmA. J Biol Chem.1998 Dec 4;273(49):32608-13.