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Brazilin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Brazilin图片
CAS NO:474-07-7
包装:20mg
市场价:3045元

产品介绍
巴西林是从几种热带硬木的心材中提取的红色染料前体。
Cas No.474-07-7
别名巴西苏木素
化学名7,11b-dihydro-6H-indeno[2,1-c]chromene-3,6a,9,10-tetrol
Canonical SMILESC1C2=CC(=C(C=C2C3C1(COC4=C3C=CC(=C4)O)O)O)O
分子式C16H14O5
分子量286.3
溶解度≥ 28.6mg/mL in EtOH
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Brazilin is a red dye precursor obtained from the heartwood of several species of tropical hardwoods. Brazilin inhibits the cells proliferation, promotes apoptosis, and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities[1][2][3].

References:
[1]. Dapson RW, et al. Brazilwood, sappanwood, brazilin and the red dye brazilein: from textile dyeing and folk medicine to biological staining and musical instruments. Biotech Histochem. 2015;90(6):401-23.
[2]. Jia Y, et al. [Effect of brazilin on apoptosis and autophagy of tongue cancer Tca8113 cells and its molecular mechanism]. Nan Fang Yi Ke Da Xue Xue Bao. 2019 Mar 30;39(3):351-356.
[3]. Weinmann D, et al, Brazilin blocks catabolic processes in human osteoarthritic chondrocytes via inhibition of NFKB1/p50. J Orthop Res. 2018 Sep;36(9):2431-2438.