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p53 and MDM2 proteins-interaction-inhibitor chiral
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
p53 and MDM2 proteins-interaction-inhibitor chiral图片
CAS NO:939981-37-0
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
100mg电议
200mg电议
500mg电议

产品介绍
手性p53 and MDM2 proteins-interaction-inhibitor是p53和MDM2相互作用的抑制剂。
Cas No.939981-37-0
别名2-[4-[[(4S,5R)-4,5-双(4-氯苯基)-2-[4-(1,1-二甲基乙基)-2-乙氧苯基]-4,5-二氢-4,5-二甲基-1H-咪唑-1-基]羰基]-1-哌嗪基]-1-(4-吗啡啉)乙酮
Canonical SMILESO=C(N1CCN(CC(N2CCOCC2)=O)CC1)N3[C@](C)(C4=CC=C(Cl)C=C4)[C@](C)(C5=CC=C(Cl)C=C5)N=C3C6=CC=C(C(C)(C)C)C=C6OCC
分子式C40H49Cl2N5O4
分子量734.75
溶解度DMSO: 50 mg/mL (68.05 mM); Water:< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

p53 and MDM2 proteins-interaction-inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2 proteins.

[1]. Chen R, et al. A Fusion Protein of the p53 Transaction Domain and the p53-Binding Domain of the Oncoprotein MdmX as an Efficient System for High-Throughput Screening of MdmX Inhibitors. Biochemistry. 2017 Jun 27;56(25):3273-3282.