Amodiaquine dihydrochloride dihydrate (Amodiaquin dihydrochloride dihydrate) 是一种 4-氨基喹啉类抗疟药，是一种有效且具有口服活性的组胺 N-甲基转移酶抑制剂。
| Cas No. | 6398-98-7 |
| 别名 | 阿莫地喹盐酸盐; Amodiaquin dihydrochloride dihydrate |
| 化学名 | 4-((7-chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenol dihydrochloride dihydrate |
| Canonical SMILES | CCN(CC1=CC(NC2=C3C=CC(Cl)=CC3=NC=C2)=CC=C1O)CC.Cl.Cl.O.O |
| 分子式 | C20H28Cl3N3O3 |
| 分子量 | 464.81 |
| 溶解度 | ≥ 70.4mg/mL in DMSO |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Amodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent.Target: histamine N-methyltransferaseAmodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine is generally well tolerated. |
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