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(S)-Indoximod
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(S)-Indoximod图片
CAS NO:21339-55-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议

产品介绍
(S)-Indoximod(1-Methyl-L-tryptophan)是吲哚胺-2,3-双加氧酶(IDO)抑制剂。(S)-Indoximod可用于癌症研究。
Cas No.21339-55-9
别名相思子碱,1-Methyl-L-tryptophan; (S)-NLG-8189
Canonical SMILESN[C@@H](CC1=CN(C)C2=CC=CC=C12)C(O)=O
分子式C12H14N2O2
分子量218.25
溶解度DMSO: 5 mg/mL (22.91 mM; ultrasonic and adjust pH to 5 with HCl)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer[1][2].

[1]. Huang GL, et, al. PEG-Poly(1-Methyl-l-Tryptophan)-Based Polymeric Micelles as Enzymatically Activated Inhibitors of Indoleamine 2,3-Dioxygenase. Nanomaterials (Basel). 2019 May 9;9(5):719. [2]. Liu X, et, al. 1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells. Int J Cancer. 2018 Sep 15;143(6):1516-1529.