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Autotaxin-IN-3
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Autotaxin-IN-3图片
CAS NO:2156655-68-2
包装与价格：
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
Autotaxin-IN-3 是 Autotaxin(ATX) 抑制剂，IC50 值为 2.4 nM，源于专利 WO2018212534A1 中，化合物 33。
Cas No.2156655-68-2
Canonical SMILESO=C(N1CCC(N=NN2)=C2C1)CC3=NN=C(C4=CN=C(NC5CC6=C(C=CC=C6)C5)N=C4)O3
分子式C22H21N9O2
分子量443.46
溶解度DMSO: 250 mg/mL (563.75 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Autotaxin-IN-3 is a Autotaxin(ATX) inhibitor with an IC50 of 2.4 nM, compound 33, sourced from patent WO2018212534A1[1].

Autotaxin is an enzyme which is responsible for the increase in lysophosphatidic acid in ascites and plasma, and it is a secretory enzyme important for converting lysophosphatidylchloine (LPC) into lysophosphatidic acid (LPA) as a bioactive signaling molecule[1].

[1]. LEE, Dae Yon, et al. NOVEL COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME. Patent O2018212534A1