Isoastilbin

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Isoastilbin

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

54081-48-0

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议

产品介绍

Isoastilbin，RhizomaSmilacisglabrae和Astragalusmembranaceus中的一种二氢黄酮醇糖苷化合物。Isoastilbin抑制葡萄糖基转移酶(GTase)的IC50值为54.3μg/mL，还抑制酪氨酸酶(tyrosinase)活性。Isoastilbin具有神经保护，抗氧化，抗微生物和抗凋亡的特性，并可用于阿尔茨海默氏病的研究。

Cas No.	54081-48-0
别名	异落新妇苷
Canonical SMILES	O[C@H]([C@@H]([C@@H](O)[C@H](C)O1)O)[C@]1([H])O[C@H]2[C@@H](C3=CC(O)=C(O)C=C3)OC4=CC(O)=CC(O)=C4C2=O
分子式	C₂₁H₂₂O₁₁
分子量	450.39
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, and also inhibits tyrosinase activity. Isoastilbin shows neuroprotective, antioxidation, antimicrobial and anti-apoptotic properties and has the potential for Alzheimer's disease research[1][21][3]. [1]. Hong Yu, et al. Protective Roles of Isoastilbin Against Alz heimer's Disease via Nrf2-mediated Antioxidation and anti?apoptosis. Int J Mol Med. 2019 Mar;43(3):1406-1416. [2]. Harlinda Kuspradini, et al. Antimicrobial activity against Streptococcus sobrinus and glucosyltransferase inhibitory activity of taxifolin and some flavanonol rhamnosides from kempas (Koompassia malaccensis) extracts. J. Wood Sci., 2009, 55(4):308-13. [3]. Batubara, Irmanida, et al. Anti-acne and Tyrosinase Inhibition Properties of Taxifolin and Some Flavanonol Rhamnosides from Kempas. Wood Research Journal ,2010, 1(1):45-9.