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NSC 207895
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NSC 207895图片
CAS NO:58131-57-0
规格:≥98%
包装与价格:
包装价格(元)
2mg电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)279.25
FormulaC11H13N5O4
CAS No.58131-57-0
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 0.4 mg/mL (1.43 mM)
Water:<1 mg/mL (slightly soluble or insoluble)
Ethanol: <1 mg/mL
Synonyms NSC-207895, NSC207895, XI-006, XI 006, XI006, NSC 207895, NSC179940, NSC-179940, NSC 179940
实验参考方法
In vitro

NSC-207895 decreases both the MDMX mRNA and protein in MCF-7 cells. NSC-207895 induces expression of p53 as well as well-characterized p53-target gene, p21 and MDM2, in a dose-dependent manner in MCF-7 cells. NSC-207895 extends the half-life of p53 from 20 to 30 minutes to more than 3 hours as revealed by cycloheximide chase assays in MCF-7 cells.

In vivo
Formulation
Dosages
Administration
Reference[1] Wang H, et al. Mol Cancer Ther, 2011, 10(1), 69-79.
生物活性

NSC-207895 is a DNA damaging agent. Molecular Systems Biology 6(1):451 December 2010