| Target： | IC50: 22 nM (cPKC-α), 30 nM (cPKC-β1), 31 nM (cPKC-β2), 24 nM (cPKC-γ), 330 nM (nPKC-δ), 160 nM (nPKC-η), 1.25 μM (nPKC-ε), 465 μM (aPKC-ζ), 38 nM (PPK), 570 nM (Protein kinase A), 95 nM (c-Syk), 86 n |
| 描述： | Midostaurin (PKC412) is an inhibitor of protein kinase C (PKC) with IC50 of 22 nM (cPKC-α), 30 nM (cPKC-β1), 31 nM (cPKC-β2), 24 nM (cPKC-γ), 330 nM (nPKC-δ), 160 nM (nPKC-η), 1.25 μM (nPKC-ε), 465 μM (aPKC-ζ), and |
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