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Lofexidine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lofexidine图片
CAS NO:31036-80-3
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议
100mg电议
200mg电议

产品介绍
Lofexidine 是选择性的、 α2 受体 激动剂,常用于缓解海洛因和其他阿片类戒断的躯体症状。
Cas No.31036-80-3
别名洛非西定
Canonical SMILESCC(C1=NCCN1)OC2=C(Cl)C=CC=C2Cl
分子式C11H12Cl2N2O
分子量259.13
溶解度DMSO: 62.5 mg/mL (241.19 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lofexidine is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal[1][2]. α2-receptor[1][2].

[1]. Vartak AP, et al. The preclinical discovery of lofexidine for the treatment of opiate addiction. Expert Opin Drug Discov. 2014 Nov;9(11):1371-7. [2]. Gish EC, et al. Lofexidine, an {alpha}2-receptor agonist for opioid detoxification. Ann Pharmacother. 2010 Feb;44(2):343-51.