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Idalopirdine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Idalopirdine图片
CAS NO:467459-31-0
包装与价格:
包装价格(元)
2mg电议
5mg电议
10mg电议
50mg电议

产品介绍
Idalopirdine (Lu AE58054) 是有效,选择性的 5-HT6 受体拮抗剂,Ki 为 0.83 nM。
Cas No.467459-31-0
别名Lu AE58054
Canonical SMILESFC1=CC(NC=C2CCNCC3=CC(OCC(F)(C(F)F)F)=CC=C3)=C2C=C1
分子式C20H19F5N2O
分子量398.37
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Idalopirdine (Lu AE58054) is a potent and selective 5-HT6 receptor antagonist with a Ki of 0.83 nM.

[1]. Arnt J, Bang-Andersen B, Grayson B, Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats. Int J Neuropsychopharmacol. 2010 Sep;13(8):1021-33. [2]. Witten L, Bang-Andersen B, Nielsen SM, Characterization of [•H]Lu AE60157 ([•H]8-(4-methylpiperazin-1-yl)-3-phenylsulfonylquinoline) binding to 5-hydroxytryptamine• (5-HT•) receptors in vivo.Eur J Pharmacol. 2012 Feb 15;676(1-3):6-11.