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GPR120 Agonist 1
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
GPR120 Agonist 1图片
CAS NO:1628448-77-0
包装与价格：
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
GPR120 Agonist 1 是一种有效、选择性的 GPR120 激动剂，具有良好的抗糖尿病作用和安全性，可作为开发候选药物。
Cas No.1628448-77-0
Canonical SMILESClC1=CC(F)=C(C2=NSC(C(F)(F)F)=C2COC3=C(F)C=C(CCC(O)=O)C=C3F)C=C1
分子式C20H12ClF6NO3S
分子量495.82
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate[1]. GPR120[1]

GPR120 Agonist 1 is a potent and selective GPR120 agonist. In GPR120 transfected HEK293 cells, GPR120 Agonist 1 displays good EC50 of 42 nM and 77 nM for human GPR120 and mouse GPR120 (the calcium flux assay), respectively[1].

[1]. Zhang X, et al. Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes. ACS Med Chem Lett. 2017 Jul 27;8(9):947-952.