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Dexetimide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dexetimide图片
CAS NO:21888-98-2
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议
100mg电议
200mg电议

产品介绍
Dexetimide ((+)-Benzetimide) 是一种高亲和力的毒蕈碱受体拮抗剂,也是强效持久抗胆碱药,可用于治疗神经抑制性帕金森病。
Cas No.21888-98-2
别名右苄替米特,(+)-Benzetimide; (S)-(+)-Dexetimide; Dexbenzetimide
Canonical SMILESO=C(N1)[C@@](C2CCN(CC3=CC=CC=C3)CC2)(C4=CC=CC=C4)CCC1=O
分子式C23H26N2O2
分子量362.46
溶解度DMSO: ≥ 100 mg/mL (275.89 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dexetimide ((+)-Benzetimide) is a high-affinity muscarinic receptor antagonist and a potent and persistent anticholinergic agent used to treat neuroleptic-induced parkinsonism[1].

[1]. Speck AL, et al. The absolute configuration and crystal structure of the anticholinergic drug dexbenzetimide. Nature. 1971 Aug 20;232(5312):575-6. [2]. MÜller-GÄrtner HW, et al. Imaging muscarinic cholinergic receptors in human brain in vivo with Spect, [123I]4-iododexetimide, and [123I]4-iodolevetimide. J Cereb Blood Flow Metab. 1992 Jul;12(4):562-70.