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Dihydro Donepezil
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dihydro Donepezil图片
CAS NO:120012-04-6
包装:5mg
市场价:1800元

产品介绍
DihydroDonepezil(DihydroE2020)是Donepezil的代谢产物。Donepezil是一种有效的特异性AChE抑制剂,对bAChE和hAChE的IC50分别为8.12nM和11.6nM。
Cas No.120012-04-6
别名盐酸多奈哌齐二氢杂质,Dihydro E2020
Canonical SMILESOC1C(CC2CCN(CC3=CC=CC=C3)CC2)CC4=C1C=C(OC)C(OC)=C4
分子式C24H31NO3
分子量381.51
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dihydro Donepezil (Dihydro E2020) is a metabolite of Donepezil. Donepezil is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively[1].

[1]. Ogura, H., et al., Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol, 2000. 22(8): p. 609-13.