DMSO : 50 mg/mL (96.24 mM; Need ultrasonic); H2O : 1 mg/mL (1.92 mM; Need ultrasonic)
存储:
Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month
研究领域:
Cancer
Target:
IC50: 1 nM (UBA1)
描述:
TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global