Compound E(Compound E(secretase inhibitor)DuPont E)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
产品介绍
CAS: | 209986-17-4 |
分子式: | C27H24F2N4O3 |
分子量: | 490.50 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 0.24 nM (β-amyloid(40)), 0.37 nM (β-amyloid(42)), 0.24 nM (Notch) |
描述: | Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively. |