CAS: | 1449236-96-7 |
分子式: | C15H12ClN3O3S |
分子量: | 349.79 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 360 nM (Cellular p97, 1 mM ATP), 370 nM (Cellular p97, 60 μM ATP)[1] |
描述: | NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50 of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively. |