CAS: | 328543-09-5 |
分子式: | C19H20N4O |
分子量: | 320.39 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | Ki: < 5 nM (PARP-1)[1]IC50: 29 nM (PARP-1, in permeabilized SW620 cells), 14 nM (PARP-1, in intact SW620 cells)[1] |
描述: | AG14361 is a potent PARP-1 inhibitor, with a Ki of < 5 nM, and in permeabilized SW620 and intact SW620 cells, the IC50 are 29 nM and 14 nM, respectively. |