包装: | 100ug |
市场价: | 2394元 |
Recombinant Human IFN-ω Protein signals through the IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. Human IFN-ω is produced by virally induced leukocytes and have similar antiviral activities on human cell lines, IFN-ω exhibits about 75% sequence homology with IFN-α, and contains two conserved disulfide bonds that are necessary for full biological activity. In addition, it was reported that IFN-ω could inhibit the growth of human tumors in vivo.
Expression host is HEK293 cells
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分子式 | |
CAS号 | |
纯度 | ≥95%, Endotoxin ≤0.05EU/ug |
溶解性(25°C) | Water Saline PBS |
储存和运输条件 | 2-8°C, dry, sealed 常温运输及临时存放 |
小鼠 | 大鼠 | 兔 | 豚鼠 | 仓鼠 | 狗 | |
重量 (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
体表面积 (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km系数 | 3 | 6 | 12 | 8 | 5 | 20 |
动物 A (mg/kg) = 动物 B (mg/kg) × | 动物 B的Km系数 |
动物 A的Km系数 |
例如,依据体表面积折算法,将化合物用于小鼠的剂量20 mg/kg 换算成大鼠的剂量,需要将20 mg/kg 乘以小鼠的Km系数(3),再除以大鼠的Km系数(6),得到化合物用于大鼠的等效剂量为10 mg/kg。