IWR-1(endo-IWR 1IWR-1-endo)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
产品介绍
CAS: | 1127442-82-3 |
分子式: | C25H19N3O3 |
分子量: | 409.44 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 180 nM (Wnt) |
描述: | IWR-1 is a Wnt pathway inhibitor with IC50 of 180 nM in L-cells expressing Wnt3A, and induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction com |