CAS: | 545380-34-5 |
分子式: | C22H20N4O |
分子量: | 356.42 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Inflammation/Immunolog/Neurological Disease |
Target: | NF-κB, 11 nM (IC50, in human Jurkat cells transfected with pNFκB-Luc); TNF-α, 7 nM (IC50, in murine splenocytes stimulated with LPS) |
描述: | QNZ shows strong inhibitory effects on NF-κB transcriptional activation and TNF-α production with IC50s of 11 and 7 nM, respectively. |