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Dithranol(Anthralin)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dithranol(Anthralin)图片
CAS NO:1143-38-0
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议

产品介绍
Dithranol (Anthralin) (Anthralin) 是一种蒽醌衍生物,具有有效的抗银屑病作用。
Cas No.1143-38-0
别名蒽林; Anthralin
Canonical SMILESO=C1C2=C(C=CC=C2O)CC3=CC=CC(O)=C13
分子式C14H10O3
分子量226.23
溶解度DMSO : ≥ 10 mg/mL (44.20 mM);Water :< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dithranol is highly effective in the treatment of psoriasis.Target: OthersDithranol accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. In addition Dithranol may act by reducing the elevated levels of cGMP that occurs in psoriasis.

[1]. http://en.wikipedia.org/wiki/Dithranol