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Rifamycin S
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rifamycin S图片
CAS NO:13553-79-2
包装与价格:
包装价格(元)
Free Sample (0.1-0.5mg)电议
10mM (in 1mL DMSO)电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
Rifamycin S 是一种醌和抗革兰氏阳性细菌 (包括 MRSA) 的抗生素。Rifamycin S 是涉及两个电子的可逆氧化还原系统的氧化形式。Rifamycin S 可以产生活性氧 (ROS) 并抑制微粒体脂质过氧化,并可用于肺结核和麻风病的研究。
Cas No.13553-79-2
别名利福霉素S
Canonical SMILESO=C1C2=C(C(C=C3NC(/C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@H]4C)=O)=O)C(C3=O)=C(O)C(C)=C2O[C@@]1(O/C=C/[C@@H]([C@H]([C@@]4([H])OC(C)=O)C)OC)C
分子式C37H45NO12
分子量695.75
溶解度DMSO: 250 mg/mL (359.32 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Rifamycin S is a quinone and an antibiotic agnet against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy[1][2][3].

[1]. Rao DN, et al. A comparative study of the redox-cycling of a quinone (rifamycin S) and a quinonimine (rifabutin) antibiotic by rat liver microsomes. Free Radic Biol Med. 1997;22(3):439-46. [2]. Kono Y. Oxygen Enhancement of bactericidal activity of rifamycin SV on Escherichia coli and aerobic oxidation of rifamycin SV to rifamycin S catalyzed by manganous ions: the role of superoxide. J Biochem. 1982 Jan;91(1):381-95. [3]. Huang H, et al. Rifamycin S and its geometric isomer produced by a newly found actinomycete, Micromonospora rifamycinica. Antonie Van Leeuwenhoek. 2009 Feb;95(2):143-8.