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D13
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
D13图片
CAS NO:321945-27-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
An acylhydrazone antifungal
Cas No.321945-27-1
Canonical SMILESO=C(N/N=C/C1=CC(Br)=CC(Br)=C1O)C2=CC=C(Br)C=C2
分子式C14H9Br3N2O2
分子量476.9
溶解度DMF: 30 mg/ml,DMSO: 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infection.

|1. Lazzarini, C., Haranahalli, K., Rieger, R., et al. Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids. Antimicrob. Agents Chemother. 62(5), e00156-00118 (2018).