Azure B

立即咨询

Azure B

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

531-55-5

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
50mg	电议

产品介绍

Azure B 是一种阳离子染料 (cationic dye)，是 Methylene blue 的主要代谢物，用于 Azure 曙红染色剂以进行血液涂片染色。Azure B 是一种高效、选择性和可逆的抑制单胺氧化酶 (MAO)-A 的抑制剂，对重组人的 MAO-A 和 MAO-B 的IC50 分别为 11 和 968 nM。Azure B 具有显著的抗抑郁作用。

Cas No.	531-55-5
别名	天青B,Azure B chloride
Canonical SMILES	CNC1=CC2=[S+]C3=C(C=CC(N(C)C)=C3)N=C2C=C1.[Cl-]
分子式	C₁₅H₁₆ClN₃S
分子量	305.83
溶解度	Soluble in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is used in making Azure eosin stains for blood smear staining. Azure B is a high-potency, selective and reversible inhibitor of monoamine oxidases (MAO)-A, with IC50s of 11 and 968 nM for recombinant human MAO-A and MAO-B, respectively. Azure B possesses significant antidepressant-like effects[1][2]. [1]. LÖhr W,et al. The azure dyes: their purification and physicochemical properties. II. Purification of azure B. Stain Technol. 1975 May;50(3):149-56. [2]. Delport A, et al. Azure B and a synthetic structural analogue of methylene blue, ethylthioninium chloride, present with antidepressant-like properties. Life Sci. 2014 Nov 11;117(2):56-66.