Cas No. | 10089-10-8 |
别名 | 巢曲菌素 |
Canonical SMILES | O=C(OC(C(C)=C(OC)C(Cl)=C1/C(C)=C/C)=C1O2)C3=C2C(Cl)=C(O)C(Cl)=C3C |
分子式 | C20H17Cl3O5 |
分子量 | 443.7 |
溶解度 | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Nidulin is a depsidone originally isolated from A. nidulans. It is active against the bacteria M. tuberculosis and M. ranoe, as well as the fungi T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC = 4 µg/ml) and has larvicidal activity toward Artemia (LC50 = 2.8 µg/ml). Nidulin is cytotoxic to MOLT-3 cells (IC50 = 21.2 µM) but not HuCCA-1, HepG2, or A549 cells (IC50s = >112.7 µM). It inhibits aromatase with an IC50 value of 11.2 µM. |