CAS: | 181629-93-6 |
分子式: | C22H17F4N3O2 |
分子量: | 431.38 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Neurological Disease |
Target: | 5-HT2A Receptor, 6.9 (pKi); 5-HT2C Receptor, 9 (pKi); 5-HT2B Receptor, 8 (pKi) |
描述: | SB228357 is a selective, potent orally active 5-HT2C/2B receptor antagonist with pKis of 6.9, 8.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. SB228357 has antidepressant/anxiolytic effect. |