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tetranor-PGEM
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
tetranor-PGEM图片
CAS NO:24769-56-0
包装与价格:
包装价格(元)
25μg电议
50μg电议
100μg电议

产品介绍
tetranor-PGEM 是前列腺素 E2 (PEG2) 的代谢物,是炎症和癌症的生物标志物,包括晚期结直肠肿瘤、卵巢癌、前列腺癌等。
Cas No.24769-56-0
别名tetranor-Prostaglandin E Metabolite
化学名9,15-dioxo-11α-hydroxy-13,14-dihydro-2,3,4,5-tetranor-prostan-1,20-dioic acid
Canonical SMILESO[C@H]1[C@H](CCC(CCCCC(O)=O)=O)[C@@H](CCC(O)=O)C(C1)=O
分子式C16H24O7
分子量328.4
溶解度50mg/mL in DMSO, or in DMF
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis.[1],[2] About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy males excrete 7-40 μg of tetranor-PGEM over a 24-hour period.[1]

Reference:
[1]. Hamberg, M. Inhibition of prostaglandin synthesis in man. Biochemical and Biophysical Research Communications 49, 720-726 (1972).
[2]. Honda, H., Fukawa, K., and Sawabe, T. Influence of adjuvant arthritis on main urinary metabolites of prostaglandin F and E rats. Prostaglandins 19, 259-269 (1980).