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GS-6207
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GS-6207图片
CAS NO:2189684-44-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
GS-6207 (GS-6207) 是一种 HIV-1 衣壳抑制剂。
Cas No.2189684-44-2
别名HIV-1衣壳抑制剂GS-6207,GS-6207
Canonical SMILESFC1=CC(F)=CC(C[C@@H](C2=NC(C#CC(S(=O)(C)=O)(C)C)=CC=C2C3=CC=C(Cl)C4=C3N(CC(F)(F)F)N=C4NS(=O)(C)=O)NC(CN5C(C(F)(F)[C@@]6([H])[C@]7([H])C6)=C7C(C(F)(F)F)=N5)=O)=C1
分子式C39H32ClF10N7O5S2
分子量968.28
溶解度DMSO: 250 mg/mL (258.19 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GS-6207 is a HIV-1 capsid inhibitor. GS-6207 shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. GS-6207 displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs)[1].

[1]. Singh K, et al. GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds. Front Microbiol. 2019 Jun 20;10:1227.