| 分子式： | C15H12ClN3 |
| 分子量： | 269.73 |
| 纯度： | >98% |
| 溶解性： | DMSO : 200 mg/mL (741.48 mM; Need ultrasonic) |
| 存储： | 4℃, stored under nitrogen. In solvent : -80℃, 6 months; -20℃, 1 month (protect from light, stored under nitrogen) |
| 研究领域： | Cancer |
| Target： | IC50: 4.9 μM (hGWLFL), 4.9 μM (hGWL-KinDom) |
| 描述： | GKI-1 is a Greatwall (GWL) kinase inhibitor with IC50s of 4.9 and 2.5 μM against hGWLFL and hGWL-KinDom, respectively. GKI-1 robustly inhibits ROCK1 with an IC50 of 11 μM, but only weakly affected PKA |
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