| CAS NO: | 156856-31-4 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 606.8 |
| Cas No. | 156856-31-4 |
| Formula | C34H54O9 |
| Solubility | Soluble in DMSO |
| Chemical Name | 3-(4-deoxy-β-xylo-hexopyranosyl)-2-hydroxy-6-[(3E,5E,8Z)-2-hydroxy-7-(hydroxymethyl)-1,1,5,9,11-pentamethyl-3,5,8-heptadecatrien-1-yl]-2H-pyran-2-one |
| Canonical SMILES | O[C@H]1C[C@@H](CO)O[C@@H](C2=C(O)OC(C(C)(C)C(O)/C=C/C(C)=C/C(CO)/C=C(C)\CC(C)CCCCCC)=CC2=O)[C@@H]1O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
Fusapyrone, a broad-spectrum antifungal metabolite, is isolated from several Fusarium species.
Structurally, fusapyrone consists of a 4-deoxy-β-xylo-hexopyranosyl C-glycosyl moiety bound to the C-6 of the 2-pyrone ring and a highly functionalized aliphatic chain. Fusapyrone exhibited low zoo-toxicity, as evidenced by a lack of toxicity against Artemia salina. Fusapyrone exerted considerable antifungal activity against several plant mycotoxigenic, pathogenic, and human pathogenic filamentous fungi, including Aspergillus flavus, Aspergillus niger, Aspergillus parasiticus, and Aspergillus fumigatus [1]. Additionally, it had been investigated as a useful candidate for the control of postharvest crop diseases, including blocking the growth of ochratoxin-producing strains of Aspergillus section Nigri in wine grapes. However, fusapyrone was found to be ineffective toward yeasts isolated from fruits and plants and not toxic to Artemia salina (brine shrimp). The mechanism of action of fusapyrone is unknown and the structure of fusapyrone was revised in 2006.
In vitro: Up to now, in vitro study of fusapyrone is still in the development stage.
In vivo: Up to now, in vivo study of fusapyrone is still in the development stage.
Reference:
[1]. Favilla, M., Pascale, M., Ricelli, A., Evidente, A., Amalfitano, C., & Altomare, C. Inhibition of Species of the Aspergillus Section Nigri and Ochratoxin a Production in Grapes by Fusapyrone. Applied and Environmental Microbiology.2008; 74(7): 2248-2253.
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