6α-Methylprednisolone 21-hemisuccinate 是一种合成糖皮质激素，广泛用作抗炎剂。
| Cas No. | 2921-57-5 |
| 别名 | 甲基泼尼松龙琥珀酸酯; Methylprednisolone hydrogen succinate |
| Canonical SMILES | O=C1C=C[C@@]2(C)C([C@@H](C)C[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC(O)=O)=O)=O)=C1 |
| 分子式 | C26H34O8 |
| 分子量 | 474.6 |
| 溶解度 | DMF: 3 mg/ml,DMSO: 5 mg/ml,DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Methylprednisolone is a synthetic glucocorticoid that has anti-inflammatory and immunosuppressant effects through the glucocorticoid receptor. The methyl group reduces specific binding to corticosteroid-binding globulin, which may allow better tissue penetration, compared to that of prednisolone. 6α-Methylprednisolone 21-hemisuccinate is a prodrug for methylprednisolone. This compound has superior water solubility compared to the active glucocorticoid. |
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