12(S)-HHTrE (12(S)-HHTrE) 是前列腺素 H2 (PGH2) 的酶产物，源自环氧合酶 (COX) 介导的花生四烯酸代谢。
| Cas No. | 54397-84-1 |
| 别名 | 12(S)-HHTrE |
| Canonical SMILES | CCCCC[C@H](O)/C=C/C=C/C/C=C\CCCC(O)=O |
| 分子式 | C17H28O3 |
| 分子量 | 280.4 |
| 溶解度 | 0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS pH 7.2: 0.8 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets. It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. 12(S)-HHTrE is a natural lipid agonist of the leukotriene B2 receptor BLT2 in vivo that induces chemotaxis of mast cells and accelerates wound closure. 12(S)-HHTrE is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH. |
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