BMS-986202 (BMS986202), a tri-deuterated compound, is potent, selective Tyk2 inhibitor with the potential to be used for IL-23-driven acanthosis, anti-CD40-induced colitis, and spontaneous lupus. It acts by binding to Tyk2 JH2 domain with IC50 of 0.19 nM, Ki of 0.02 nM,and exhibits >10,000-fold over 273 kinases and pseudokinases.
纯度:≥98%
CAS:1771691-34-9