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Meclofenamate Sodium
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Meclofenamate Sodium图片
CAS NO:6385-02-0
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议
100mg电议
200mg电议

产品介绍
甲氯芬那酸（Meclofenamate）钠是一种非甾体抗炎药（NSAID），被批准用于关节炎（骨关节炎和类风湿）、镇痛（轻度至中度疼痛）、痛经和大量月经失血（月经过多）。
Cas No.6385-02-0
别名甲氯灭酸钠,Meclofenamate sodium
Canonical SMILESO=C(O[Na])C1=CC=CC=C1NC2=C(Cl)C=CC(C)=C2Cl
分子式C14H10Cl2NNaO2
分子量318.13
溶解度250mg/mL in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Meclofenamic acid sodium is a nonsteroidal anti-inflammatory drug (NSAID) approved for use in arthritis (osteo and rheumatoid), analgesia (mild to moderate pain), dysmenorrhea, and heavy menstrual blood loss (menorrhagia). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor[1][2][3].

[1]. Conroy MC, et al. Pharmacology, pharmacokinetics, and therapeutic use of meclofenamate sodium. Clin J Pain. 1991;7 Suppl 1:S44-8. [2]. Eleftheriou CG, et al. Meclofenamic acid improves the signal to noise ratio for visual responses produced by ectopicexpression of human rod opsin. Mol Vis. 2017 Jun 16;23:334-345. eCollection 2017. [3]. Huang Y, et al. Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5. Nucleic Acids Res. 2015 Jan;43(1):373-84.