化学性质
Physical Appearance | A light to dark tan solid |
Storage | Store at -20°C |
M.Wt | 331.28 |
Cas No. | 131436-22-1 |
Formula | C16H13NO7 |
Solubility | Limited solubility, soluble in DMSO |
Chemical Name | (9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxodibenzofuran-4-carboxamide |
Canonical SMILES | CC(=O)C1=C(C=C2C(C1=O)(C3=C(C=C(C(=C3O2)C(=O)N)O)O)C)O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) and JAK3 (IC50values are 11, 31 and 116 nM for Mnk2, JAK3 and Mnk1 respectively). Blocks eIF4E phosphorylation; exhibits antiproliferative and proapoptotic activity in cancer cellsin vitro. Also inhibits Pkc1. Orally bioavailable.