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Cyclosporin B
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Cyclosporin B图片
CAS NO:63775-95-1
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
环孢菌素 B 是一组具有免疫抑制活性的非极性环状寡肽。
Cas No.63775-95-1
别名环孢菌素B
Canonical SMILESO[C@@H]([C@](C(N[C@H](C(N(CC(N(C)[C@H](C(N[C@@H](C(C)C)C(N(C)[C@H]1CC(C)C)=O)=O)CC(C)C)=O)C)=O)C)=O)([H])N(C([C@H](C(C)C)N(C([C@@H](N(C([C@H](CC(C)C)N(C([C@H](NC([C@@H](NC1=O)C)=O)C)=O)C)=O)C)CC(C)C)=O)C)=O)C)[C@H](C)C/C=C/C
分子式C61H109N11O12
分子量1188.6
溶解度DMF: 20 mg/ml,DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml,DMSO: 3 mg/ml,Ethanol: 14 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cyclosporin B is a minor cyclopeptide metabolite produced by T. polysporum and other deuteromycota with diverse biological activities. It inhibits the growth of T lymphoma cells in a concentration-dependent manner. It is toxic to mosquito (C. pipiens) larvae (LC50 = 3.0 μg/ml). Cyclosporin B also inhibits P-glycoprotein (P-gp) activity in vitro with an IC50 value of 4.7 μM.