化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 286.72 |
Cas No. | 119615-63-3 |
Formula | C14H11ClN4O |
Synonyms | Loprinone (Hydrochloride) |
Solubility | insoluble in EtOH; ≥13.2 mg/mL in H2O with gentle warming; ≥52.1 mg/mL in DMSO with gentle warming |
Chemical Name | 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile;hydrochloride |
Canonical SMILES | CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Olprinone is a selective phosphodiesterase 3 (PDE3) inhibitor. Olprinone is used as cardiotonic agent with positive inotropic and vasodilating effects. Olprinone has been reported to improve microcirculation and attenuate inflammation. Olprinone is often used to increase cardiac output after cardiopulmonary bypass (CPB). Olprinone was infused at a rate of 0.2 μg/kg/min when weaning from CPB was started. Olprinone has also shown potent antioxidative and anti-inflammatory effects in the meconium-induced oxidative lung injury.