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15-Lipoxygenase Inhibitor 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
15-Lipoxygenase Inhibitor 1图片
CAS NO:928853-86-5
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议
10mg电议

产品介绍
15-Lipoxygenase Inhibitor 1 是 15-lipoxygenase 的选择性抑制剂,IC50 为 18 μM. 15-脂氧合酶抑制剂 1 对大豆 15-脂氧合酶 (SLO) 和人 15-脂氧合酶-1 (15-LOX-1) 的 IC50 分别为 19.5 μM 和 19.1 μM。 15-Lipoxygenase Inhibitor 1 具有研究前列腺癌的潜力。
Cas No.928853-86-5
Canonical SMILESCC1=C(NC(C=CC=C2)=C2S3)C3=NC(N4CCN(C)CC4)=N1
分子式C16H19N5S
分子量313.4
溶解度Chloroform: >5mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lipoxygenases (LOs) are non-heme iron-containing dioxygenases that catalyze the oxidation of polyunsaturated fatty acids to generate unsaturated fatty acid hydroperoxides. The immediate products of 15-LO fatty acid oxidation act as mediators in inflammation, thrombosis, and cancer. 15-Lipoxygenases (15-LO) inhibitor 1 is a heterocyclic pyrimidobenzothiazine compound that inhibits 15-LO with an IC50 value of 18 µM. The inhibitor appears to act as an antioxidant, interfering with the redox cycle of 15-LO.