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2'-O-Methylguanosine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2'-O-Methylguanosine图片
CAS NO:2140-71-8
包装与价格：
包装价格(元)
250mg电议
500mg电议
1g电议

产品介绍
2'-O-甲基鸟苷是在 tRNA 鸟苷-2'-O-甲基转移酶的作用下在 tRNA 中产生的修饰核苷。
Cas No.2140-71-8
别名2'-甲氧基鸟苷
Canonical SMILESO=C1C2=C(N([C@H]3[C@H](OC)[C@H](O)[C@@H](CO)O3)C=N2)N=C(N)N1
分子式C11H15N5O5
分子量297.3
溶解度0.1 M HCl: 10 mg/ml,DMF: 50 µ g/ml,DMSO: 12 mg/ml,Ethanol: 50 µ g/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2'-O-Methylguanosine is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA. 2'-O-Methylguanosine can also be found in rRNA. Normal and modified nucleosides, including 2'-O-methylguanosine, have been shown to be secreted by a natural suppressor cell line and induce apoptosis in K562/Molt4 target cells.