Lonicerin 是一种抗 algE（藻酸盐分泌蛋白）类黄酮，对 P.
| Cas No. | 25694-72-8 |
| 别名 | 忍冬苦苷 |
| Canonical SMILES | O[C@H]([C@H]1O[C@@]2([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O2)[C@H](O)[C@@H](CO)O[C@H]1OC3=CC(O)=C(C(C=C(C4=CC(O)=C(O)C=C4)O5)=O)C5=C3 |
| 分子式 | C27H30O15 |
| 分子量 | 594.5 |
| 溶解度 | DMF: 50 mg/ml,DMSO: 50 mg/ml |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Lonicerin is a flavonoid that has been found in L. japonica and has diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties. Lonicerin inhibits xanthine oxidase (IC50 = 37.4 µg/ml) and scavenges 2,2-diphenyl-1-picrylhydrazyl , hydroxyl, and superoxide radicals (IC50s = 9.2, 236.8, and 143.9 µg/ml, respectively). It reduces paw edema in a mouse model of C. albicans cell wall- and complete Freund's adjuvant-induced arthritis when administered at doses of 1 and 2 mg/kg three times every other day. It also decreases nitric oxide (NO) production and T cell proliferation in vitro when used at concentrations of 20 and 40 µg/ml, respectively. Lonicerin is neuroprotective against glutamate-induced neurotoxicity in rat primary cortical neurons. |
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