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JG-98
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
JG-98图片
CAS NO:1456551-16-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
JG-98是一种热休克蛋白70(Hsp70)抑制剂,具有抗癌活性。
Cas No.1456551-16-8
别名3-苄基-2-((Z)-((E)-5-(6-氯-3-甲基苯并[D]噻唑-2(3H)-亚基)-3-乙基-4-氧代噻唑啉-2-亚基)甲基)噻唑-3-鎓氯化物
Canonical SMILESCN1/C(SC2=CC(Cl)=CC=C12)=C3S/C(N(CC)C\3=O)=C\C4=[N+](C=CS4)CC5=CC=CC=C5.[Cl-]
分子式C24H21Cl2N3OS3
分子量534.54
溶解度DMSO : 5 mg/mL (9.35 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

JG-98 is a heat shock protein 70 (Hsp70) Inhibitor with anti-cancer activities[1][2]. Heat shock protein 70[1]

JG-98 inhibits the breast cancer cell lines MDA-MB-231 and MCF-7 with EC50 values of 0.4 and 0.7 μM, respectively[1].

[1]. Yaglom JA, et al. Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and findingsynergistic drug combinations. Sci Rep. 2018 Feb 14;8(1):3010.