Lovastatin Hydroxy Acid (sodium salt) (Mevinolinic acid sodium) 是一种高效的 HMG-CoA 还原酶抑制剂,Ki 为 0.6 nM。
Cas No. | 75225-50-2 |
别名 | 洛伐他汀钠,Mevinolinic acid sodium |
Canonical SMILES | C[C@H]1C=CC2=C[C@H](C)C[C@H](OC([C@@H](C)CC)=O)[C@]2([H])[C@H]1CC[C@@H](O)C[C@@H](O)CC([O-])=O.[Na+] |
分子式 | C24H37O6•Na |
分子量 | 444.5 |
溶解度 | DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
文献引用 | |
产品描述 | Lovastatin hydroxy acid is a potent and competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM). It is the more potent, open ring, hydroxy acid form of its prodrug, lovastatin . |