| CAS NO: | 515-13-9 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Physical Appearance | A liquid |
| Storage | Store at -20°C |
| M.Wt | 204.35 |
| Cas No. | 515-13-9 |
| Formula | C15H24 |
| Solubility | ≥1 mg/mL in H2O with ultrasonic; ≥22.2 mg/mL in EtOH; ≥30.7 mg/mL in DMSO |
| Chemical Name | (1S,2S,4R)-1-methyl-2,4-di(prop-1-en-2-yl)-1-vinylcyclohexane |
| Canonical SMILES | C=C[C@]1([C@@H](C[C@@H](CC1)C(C)=C)C(C)=C)C |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
β-elemene is extracted from natural plant turmeric and has antitumor activity. β-elemene can induce apoptosis[1].
In VSC4.1 motor neuron cell line, β-elemene (20 μg/ml) can enhance cell viability by activating phosphorylation of the PI3K/AKT/mTOR pathway. β-elemene reduces CoCl2-induced cell death and apoptosis [2].
In SCI rat models, β-elemene increases motor neuron survival rate and reduces neuronal apoptosis in spinal cord ventral horn neurons. β-elemene can accelerate the recovery of motor behavior after spinal cord injury. In addition, β-elemene reduced the secretion of interleukin-6 and interleukin-1β[2].
References:
[1]. Ross S A, and ElSohly M A. The volatile oil composition of fresh and air-dried buds of Cannabis sativa. J. Nat. Prod, 1996, 59(1): 49-51 .
[2]. Wang J, Li H, Ren Y, et al. Local Delivery of β-Elemene Improves Locomotor Functional Recovery by Alleviating Endoplasmic Reticulum Stress and Reducing Neuronal Apoptosis in Rats with Spinal Cord Injury. Cell Physiol Biochem, 2018, 49(2): 595-609.
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