Mycophenolate mofetil (RS 61443) hydrochloride 是一种免疫抑制剂，一种非竞争性、选择性和可逆的 I/II 型肌苷单磷酸脱氢酶 (IMPD) 抑制剂，IC50 分别为 39 nM 和 27 nM。
| Cas No. | 116680-01-4 |
| 别名 | RS 61443 hydrochloride; TM-MMF hydrochloride |
| 化学名 | 2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate;hydrochloride |
| Canonical SMILES | CC1=C(C(=C(C2=C1COC2=O)O)CC=C(C)CCC(=O)OCCN3CCOCC3)OC.Cl |
| 分子式 | C23H32ClNO7 |
| 分子量 | 469.96 |
| 溶解度 | ≥ 83.3mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Mycophenolate Mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. |
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