CAS NO: | 2230810-28-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
Cas No. | 2230810-28-1 |
Canonical SMILES | O=C(CC1=C(C)NC2=C1C=C(OC)C=C2)N(CCN(CC3CCOC3)C4)C4C5=NC=C(N5)C6=CC(C=CC=C7)=C7C=C6 |
分子式 | C34H37N5O3 |
分子量 | 563.69 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1]. EC50: 5 nM (Trypanosoma brucei)[1] Tuberculosis inhibitor 1 is selective over other parasites, such as Trypanosoma cruzi and Plasmodium falciparum (T. cruzi EC50 8120 nM, P. falciparum EC50 3624 nM)[1]. [1]. Ferrigno F, et al. Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitorsof Trypanosoma brucei growth in vitro. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3689-3692. |